What is the best way to lose weight? Despite what quick weight loss diet books may say, the only sensible way to lose weight and maintain a healthy weight permanently is to eat less and balance your food intake with physical activity. A healthy diet rich in fresh fruits and vegetables, whole grains and fat-free or low-fat dairy products, along with regular physical activity, can help most people manage and maintain weight loss for both cardiovascular health and appearance. It is urged that people should take a safe and proven route to losing and maintaining weight — by following our guidelines for healthy, nutritionally balanced weight loss for a lifetime of good health.